SottoPelle® Bio-identical Hormone Therapy

What is SottoPelle® bio-identical hormone therapy?

It is the most convenient and effective method of hormone replacement available. Thoroughly documented and researched in medical journals, the therapy involves the simple and painless insertion of bio-identical hormone pellets under the skin. The pellet implants are low-dose, customized to suit the physiological needs of each individual patient and are approximately the size of a Tic Tac. When blood flows over them they begin to release the correct amount of tester one and estradiol into the blood stream. More testosterone and/or estradiol is released into the blood stream whenever the body needs it, for example, during exercise or periods of stress. This delivery method allows your body to recognize the hormones and flourish with them by providing the ability to control the release of the hormone just as it did when the ovaries and testicles were working normally.
SottoPelle was developed by Dr. Gino Tutera, widely recognized as a pioneer and leader in the field of bio-identical hormone therapy and who specializes in the treatment of hormone deficiency. Dr. Tutera developed SottoPelle Hormone Therapy based on the use of subcutaneous pellets – the most effective hormone delivery system available. At Xanadu Med Spa, we have been trained by Dr. Tutera’s office in this therapy and obtain from Dr. Tutera’s company both the same sourcing of the hormone pellets and the tools to customize the therapy to each patient’s hormone needs.

Committed to Quality Healthcare Treatments

You can count on our experienced providers to boost your health through safe and proven therapies. Get quality SottoPelle hormone treatments to relieve you from your health problems. You'll be surprised to learn that we have minimal office waiting time. Our friendly and courteous staff will deliver personalized services at our clinic. Learn more about SottoPelle therapy.

What are some of the benefits pellet hormone replacement therapy offer?

Benefits from our hormone therapies

  • Improvement in energy levels
  • Restored or increased sexual drive
  • Consistency in moods (no more roller coaster effect)
  • Relief from anxiety and depression
  • Weight improvement - decrease in fat mass, increase in lean muscle mass in both men and women
  • Increase in muscle strength and physical performance
  • Improved cognition - estrogen is used that passes the blood-brain barrier improving thinking, concentration, and prevents dementia

More Uses of this Therapy
  • Relief from hot flashes
  • No increased risk of breast cancer - 20 years of data support
  • Cardio protective - improvement in lipid panels, causes dilation of the blood vessels that feed the heart and no increased risk of blood clots
  • Improvement in bone density - a four-fold increase in bone density over oral estrogen
  • New treatment strategy for Parkinson’s disease
  • Transgender Patients


I get horrible headaches; will pellet hormone therapy help me?

I get horrible headaches; will pellet hormone therapy help me?

How often will I need to come back to the office to receive pellets?

It depends on the person, but on average from three to four months.

What about other types of bio-identical therapies?

Unlike other methods out there, these pellets are placed under the skin. Other forms, including creams, patches, injections, and even miniscule capsules go through the liver and can cause a roller coaster effect. The pellets used in SottoPelle go through the blood stream, don’t go through the liver and can deliver a constant stream of hormones into your bloodstream twenty-four hours a day, seven days a week.
Not all hormone replacement therapy pellets are created the same either. Some hormone therapy pellets use fillers or more pure ingredients and compounding methods. The physician’s experience and training in diagnosis and pellet insertion procedures can also make a significant difference in the efficacy of your treatment. Years of research went into developing our SottoPelle method. In the end, it was uniquely formulated to work with your body's chemistry to support individual hormonal balance and optimum health. SottoPelle only uses the right kind of natural hormone (biologically identical), using the proper delivery system (quality pellets placed under the skin), in the proper amounts (through accurate testing, analysis and individualized to your hormonal needs) that will work for three to six months, and for some, even longer!

Why doesn't my doctor suggest natural hormone replacement therapy as an option?

The great majority of physician training is on synthetic hormones. More than likely they were never trained on the use of biologically identical hormone therapies.

How long will it take for the hormones to get into my system and work?

Most females report that they begin to experience improvement within several days of receiving their pellets. Testosterone pellets for men may take two weeks to express their benefits.

As a woman, do I still need estrogen in my hormone replacement therapy?

Estrogen is the most important hormone for a woman to protect her against heart attack, stroke, osteoporosis and Alzheimer's. Synthetic estrogen taken orally does not offer the universal benefits or the same benefits as being on bio identical estrogen.

Are there any side effects or complications?

Side effects in both men and women are rare. In women, transient breast tenderness lasting 7-10 days may occur with the first insertion, but rarely with repeat treatments. Acne and hair loss are rare occurrences from testosterone therapy. The growth of facial hair is also rare and occurs no more frequently than what happens in post menopausal women on no hormones. In men, the side effects are also rare, but may include decreased sperm count, decreased testicular mass and possible prostate enlargement. It should be noted that these side effects occur much more frequently with the use of synthetic hormone replacement therapies.

What If My Primary Care Physician Or My Gynecologist Says That There Is ‘No Data’ To Support The Use Of Pellet Implants? And Is It Safe?

It’s up to you to do your research and make an informed decision. Pellet therapy has been in use since 1935 Europe and the 1950’s in the United States, and there is plenty of evidence to support the long-term safety and benefits of hormone therapy using pellet implants. Bio-identical hormone pellet therapy is currently being administered safely to women and men in five continents, and has been studied for over 80 years, not only to determine safety and efficacy, but to study its role in the prevention of diseases, such as breast cancer, heart disease, osteoporosis, Alzheimer’s dementia, Type 2 diabetes and many others.

Please call our office today at 970-482-1889 to schedule your SottoPelle therapy consultation.

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Dr. Oz Video with Dr. Tutera on YouTube